The Digital Biology Project explores the digital nature of biology at the molecular scale. We focus on the role of the hydrophobic effect in protein/ligand associations.
Protein interactions are discrete in nature even though hydrophobic effects are non-specific in general. There is a useful analogy with the duality between the analog and digital nature of computer chips. We refer to this study as the Digital Biology Project. We pursue basic biophysical issues but we also apply our ideas to biomedical problems, e.g., to contribute to the understanding of antibody binding and to drug design.
Our collaborators include